While researching the topic of unexplained infertility, I stumbled across an interesting article on advancedfertility.com. To illustrate all of the things that “must happen perfectly in order to get pregnant and have a baby,” they made an oversimplified list of the science involved in a successful conception.
What must happen for a successful conception:
- The hormones that stimulate egg development must be made in the brain and pituitary and be released properly
- The egg must be of sufficient quality and be chromosomally normal
- The egg must develop to maturity
- The brain must release a sufficient surge of the LH hormone to stimulate final maturation of the egg
- The follicle (eggs develop in structures called follicles in the ovaries) must rupture and release the follicular fluid and the egg
- The tube must “pick up” the egg
- The sperm must survive their brief visit in the vagina, enter the cervical mucous, swim to the fallopian tube and “find” the egg
- The sperm must be able to get through the cumulus cells around the egg and bind the shell (zona pellucida) of the egg
- The sperm must undergo a biochemical reaction and release their DNA package (23 chromosomes) into the egg
- The fertilized egg must be able to divide
- The early embryo must continue to divide and develop normally
- After 3 days, the tube should have transported the embryo down into the uterus
- The embryo must continue to develop and expand into a blastocyst
- The blastocyst must hatch out of its shell
- The endometrial lining of the uterus must be properly developed and receptive
- The hatched blastocyst must attach to the endometrial lining and “implant”
- Many more miracles in early embryonic and fetal development must then follow…
A weak link anywhere in this chain will cause failure to conceive
The above list is very oversimplified, but the point is made. There are literally hundreds of molecular and biochemical events that have to happen perfectly in order to have a pregnancy develop.
Wow! The way I see it is that those suffering with unexplained infertility should not be considered “unfortunate,” but that each time a baby is successfully conceived should be considered a miracle! This reminds me of my college biology class. I remember being completely blown away by the many “miracles” that have to occur in order or a baby to be conceived, carried through pregnancy and then delivered. Among other things, it definitely strengthened my faith in my Creator God!
All of this to say, there are many factors involved in conception and pregnancy, and if any one of them does not function properly, infertility occurs. Unexplained infertility simply means that the doctor cannot find that “weak link” that is not properly functioning. During his studies and through years of experience, Dr. Thompson, founder of ToConceive, found that sexual arousal and inadequate normal vaginal lubrication are probably main causes of unexplained infertility. This is because of the lack of optimum sperm support and the lack of adequate sperm capacitation necessary for ovum fertilization. ToConceive is a natural and inexpensive product that is designed to do just that- increase the female’s sexual arousal and aid the body in producing an adequate supply of vaginal lubrication. It also aids in male subfertility issues (oftentimes also unexplained) as it capacitates the sperm to allow it to fertilize the ovum. Before heading down the road to IVF, why not give it a try and see if your diagnosis of unexplained infertility can be cured!
For a much more in-depth explanation of the science behind conception, please visit http://www.keytoconceive.com.